Monday, 17 June 2013

Introduction to Biotechnology

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What is Biotechnology ??
 
Biotechnology, by definition, is manipulation of biological systems also refers to the use of microorganisms such as bacteria or biological substances such as enzymes to perform industrial or manufacturing process.
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According to Webster dictionary; the aspect of technology concerns with the application of biological and engineering data to problems relating to the mutual adjustment man and machine.

 
Spinks (1980) define biotechnology as the application of biological organisms, systems or processes to manufacturing and industries.
 
According to the European Federation of Biotechnology (1981); the integrated use of biochemistry, microbiology and engineering sciences in order to achieve industrial application.


According to Canadian development plan (1981); the utilization of a biological process by plant, animal or microbes or their constituents to provide goods and services.


Bull et al., 1982; the application of scientific and engineering principles to process material by biological agents to provide goods and services.

 

the wider definition of biotechnology is :


the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services.

 
Classes of Biotechnology 


Medical biotechnology.



Ecological biotechnology.



Bioprocess.



Pharmaceutical and industrial biotechnology.



Farming biotechnology.




How Old Biotechnology
Biotechnology is very old:

     - Beer, Bread, and Wine making are centuries old.


     - 1637 Van leeuwenhoek- First observation of live microorganisms through magnifying
        lenses.


     - 1665  Robert Hook- First observation of cells. 

  

     - 1800s- Traditional breading - plants and animals.


     - 1850s- Producing Vaccines.


     - Late 1880s-  Gregor Mendle discovered the laws governing the genetic  inheritance 
       
of traits by scientific experimentation.
    

     - 19940s- producing antibiotics.


     - 1960s- Producing high-yielding rice and wheat varieties.


     - 1990s- Developing genetically modified plants and animals.


 How Old is Modern Biotechnology

Events affected the development of modern Biotechnology :
 
-1940s Beadle and Tatum : 

    One gene one (enzyme) protein hypothesis.


-1944 Oswald Avery and Hershy-Chase:

     DNA is the genetic material.
 

-1953- Watson and Crik :

  Discovered the DNA double helix.


-1973- Boyer and Cohen:

    Discovered Gene splicing and gene cloning.


-1982 Eli Lilly : First recombinant protein (Insulin).


-1986-Kery Millus : invented the thermocycler (Polymerase Chain Reaction-PCR).


- 2001- Human Genome Project.


 

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